About Eosinophils:
Eosinophils
are specific resistant cells
The
eosinophil is a specialized cell of the immune system. This proinflammatory
white blood cell (WBC) generally has a nucleus with two lobes (bilobed) and
cytoplasm filled with just about 200 large granules containing enzymes and
proteins with different functions.
The white
blood cells (WBC) are stained with Hematoxylin and Eosin (H&E). Hematoxylin
and Eosin staining a general method used in histology. The hematoxylin marks
the nuclei of cells (purple); the control center of the cell is where the DNA
located. The eosin stains proteins (pink). The white blood cells are
eosinophils (nucleus with 2 lobes) and neutrophils (nucleus with 2 to 5 lobes).
The strong pink stains in the eosinophils is the reason why these cells were
named "eosinophils", meaning "eosin loving".
High-magnification
H&E staining of blood eosinophils the bright pink marks the mediator- and
protein-stuffed granules that break open when the eosinophil is turn on. The
granule contents poisonous to both invaders and a person's own cells and
tissues.
Eosinophil maturation
Eosinophils
are formed completely in the bone marrow where they spend 8 days in the progression
of maturation before moving into the blood vessels. Eosinophils travel through the vessels for 8
to 12 hours before they to finish arrive at aim tissues, they remain for 1 to 2
weeks. Interleukin 5 (IL-5) appears to be the major growth factor for this type
of cell.
Eosinophils
have many diverse functions:
The
functions of the eosinophil are different, some of which are very similar to
other white blood cells (WBC). They are implicated in numerous inflammatory
processes, particularly allergic disorder.
In adding up, eosinophils might have a physiological function in organ
formation.
Eosinophilic
functions includes: movement to inflamed areas, trapping substances, killing
cells, antiparasitic and bactericidal activity, participating in immediate
allergic reactions, and alter inflammatory replys.
The
eosinophil is a specialized cell of the immune system first recognized by “Paul
Ehrlich” around 130 years before. The majority of our existing knowledge regarding
this type of white blood cell came during the latter half of the twentieth
century as the eosinophil was wrongly believed to be a precursor of red blood
cells during the early 1950's.
Structure
The eosinophil generally has a nucleus by two
lobes (bilobed), and cytoplasm filled with approximately 200 large granules
containing enzymes and proteins with different functions.
Development:
Eosinophils are formed completely in the bone
marrow where they spend about 8 days in the process of maturation before moving
into the blood vessels. They go throughout the vessels for 8 - 12 hours before
they finally arrive at target tissues, wherever they remain for 1 - 2 weeks.
Interleukin 5 (IL-5) is a major growth factor for this type of cell.
Function
Eosinophils are proinflammatory white blood
cells (WBC) that have lots of functions. They are implicated in frequent
inflammatory processes, particularly allergic disorder. The function of the
eosinophil are diverse, which are extremely similar to other white cells. Known
functions contain movement to inflamed areas, killing cells, trapping
substances, antiparasitic and bactericidal activity, contribute in allergic
reactions, and modulating inflammatory reaction.
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